Effect 
Antibacterial, moisturizing 
International nonproprietary name 
Chloramphenicol 
Dosage form 
Eye drops 0.5% 
Pharmacological properties of 
Pharmacokinetics 
When backfilling into the eyes of a therapeutic concentration of chloramphenicol is created in the vitreous body, cornea, iris, aqueous humor eyes. In the lens of the eye does not get chloramphenicol. Due to the presence of polyvinylpyrrolidone, the drug has a high viscosity and good adhesive properties with respect to the front surface of the eye, increasing duration of contact with the cornea of ​​the solution, prolonged therapeutic effect of the drops. Formed even, continued for a long time prerogovichnaya tear film, which is not washed off by a long blink and do not cause visual impairment. 
Pharmacodynamics 
Chloramphenicol is a broad-spectrum antibiotic, effective against many Gram-positive and gram-negative bacteria, including a family of intestinal bacteria, bacillus influenza, etc. The mechanism of antimicrobial activity is associated with inhibition of RNA synthesis at 50-S ribosomes and the inhibition of the substance of protein synthesis. It is effective against bacterial strains resistant to penicillin, tetracycline, sulfonamides. Active against Escherchia Coli, Haemophilus influenza, Klebsiella pneumonia, Enterobacter, and some types of Neisseria, Staphylococcus aureus, Steptococus spp. Effective against Pseudomonas aeruginosa, Serratia marcescens. Bacteriostatic action. Habituation of microorganisms to levomitsetinu develops slowly. 
Indications for use 
Conjunctivitis, keratitis, keratoconjunctivitis, corneal ulceration, blepharitis, blefarokonyunktivity.